Heart disease is the nation’s leading killer. The heart can be damaged suddenly or over time. Why does the normal pattern of electrical conductivity in the heart sometimes go awry or stop abruptly? How do arteries become blocked? What strategies might scientists develop to help correct these problems, as well as to repair the heart after injury as occurs during a heart attack by reducing scar tissue in the heart that can lead to heart failure and facilitating the regeneration and/or repair of normal cardiac cells? Scientists at the Virginia Tech Carilion Research Institute’s Center for Heart and Regenerative Medicine Research aim to improve understanding of exactly how the heart functions, why it sometimes fails to work properly, and what to do to repair any damage.