Research Areas in Cardiovascular Science

Arrhythmia

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Atrial Fibrillation

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Biological Machinery

When cells miscommunicate during development, the results can be catastrophic. Children and adults alike end up with a host of diseases, including cancer and heart defects.

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Cardiac Conduction

Connexins, the subunit proteins of gap junctions, allows the spread of electrical activity between cardiac myocytes for the purpose of coordinating uniform and synchronized contraction. They may play a role in how conduction of electrical impulses in the heart occurs via an ephaptic mechanism.

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Cardiomyopathy

Cardiomyopathy refers to a group of diseases affecting the heart--the cause of which can be genetics, lifestyle choices, or unknown. To restore normal cardiac function to diseased hearts, scientists are working to identify new targets for therapeutic interventions at the subcellular level.

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Sudden Cardiac Death

Sudden cardiac death is a significant cause of mortality in the United States and around the world. There is an increasing awareness that sudden cardiac death is linked to genetic mutations in cardiac proteins, or changes in those same proteins during diseases such as heart failure, ischemia, or diabetes.

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Vasculature

Blood vessels deliver oxygen and distribute inflammatory cells to nearly every tissue in the human body, among other essential functions. Regulation of vascular growth must therefore be tightly controlled, and when this regulation is disrupted, numerous diseases can occur or become worsened such as cancer growth and metastasis.

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