Active Grants Related to Cancer Research

  • Clinical trial of new drug in dogs to treat brain cancer in humans. PI: Robert Gourdie. VBHRC.
  • Therapeutic disruption of connexin-43-mediated microtubule regulation to target glioblastoma cancer stem cells. PI: Robert Gourdie. National Institutes of Health.
  • Tunable microchip sorting of BRCA1 nuclear assemblies. PI: Deborah Kelly. National Institutes of Health: National Cancer Institute.
  • Hotspot analysis of the breast cancer susceptibility protein. PI: Deborah Kelly. National Institutes of Health: National Cancer Institute.
  • Multi-scale imaging of breast cancer proteins during DNA repair. PI: Deborah Kelly. National Institutes of Health: National Cancer Institute.
  • Selectively targeting a PI3K subunit to overcome temozolomide resistance and treat recurrent glioblastoma. PI: Zhi Sheng. National Institutes of Health: National Cancer Institute.
  • Role of chloride channels and transporters in tumor-associated epilepsy. PI: Harald Sontheimer. National Institutes of Health: National Institute of Neurological Disorders and Stroke.
  • Novel therapeutic approach in treatment of glioblastoma using sustained delivery of connexin-43 carboxy-terminal peptide encapsulated in biodegradable nanoparticles in combination with temozolomide. PI: Robert Gourdie. National Institutes of Health.
  • Targeting colon cancer stem cell survival with a novel connexin-43 mimetic peptide. PI: Samy Lamouille. American Society of Colon and Rectal Surgeons.