Dr. Horn joined Virginia Tech’s Office of the Vice President of Health Sciences and Technology in March 2018 as the university’s first Associate Vice President of Clinical Research Collaboratives. She also holds appointments in the VTC Research Institute and the Department of Population Health Sciences. Arriving from George Washington University where she was the research dean in the School of Public Health, Dr. Horn is a nationally recognized leader in her field. Dr. Horn also has a diverse research funding portfolio from federal, state, and private agencies investigating tobacco and other drug abuse. Over 16 years of continuous federal funding afforded her the opportunity to develop an internationally-recognized program of research in youth and young adult smoking cessation. A significant part of that program is the Not On Tobacco (N-O-T) teen smoking cessation program, which she co-developed during her time at West Virginia University, where she was a Professor of Community Medicine and Associate Director of the Mary Babb Randolph Cancer Center. N-O-T was formally adopted by the American Lung Association (ALA) in 1998 and continues today across the US helping thousands of youth stop smoking. N-O-T is a multi-session, group-based, gender-tailored intervention, most frequently implemented in school-based settings by ALA-certified facilitators. A National Survey of Tobacco Cessation Programs for Youths by Curry and colleagues (2007) cited N-O-T as the most widely used teen cessation program in the US. Curry’s study profiled 591 programs in 408 US counties. Demonstrating national reach, the study found that N-O-T was the most commonly used packaged program and was reported as the source program by 30% of school administrators. N-O-T has been evaluated by the National Registry of Effective Programs and has received several awards. The program has been federally recognized as a Substance Abuse and Mental Health Administration evidence-based Model Program, a National Cancer Institute Research Tested Intervention Program, Centers for Disease Control and Prevention Adoptable Program, and an Office of Juvenile Justice and Delinquency Prevention Model Program. Dr. Horn also led the development of an American Indian N-O-T adaptation and a self-paced, Internet-based N-O-T Power Guide. N-O-T is also available in Spanish. While N-O-T studies show positive impact on teens, Horn continues to investigate approaches to improve teens’ odds of quitting smoking. Horn and her team published as study in the Journal of Adolescent Health (2013) demonstrating the importance of adding physical activity to teen smoking cessation. These studies caught the attention of the popular media sounding in media venues around the world, including TIME, CNN, USAToday, and the NY Times. Dr. Horn continues to grow her tobacco control research portfolio at VT partnering not only with VTCRI colleagues, but with other major universities and organizations across the region. Her continued impact on the field is evidenced by her emerging studies on poly tobacco use, ENDs, and harm reduction and her recent R01 grant from the National Cancer Institute determining the social and environmental conditions that maximize teen smoking cessation outcomes. Since arriving at VT, Horn is also circling back to some of her early pivotal work in drug abuse prevention reinventing programs and innovations to address the opioid crisis in central Appalachia. Horn has received several awards in recognition of the research, including the Award of Research Innovation for N-O-T from the Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Prevention Research Centers (2004). Dr. Horn is extensively published and a noted scientist in her field; to that end, she is the current chairperson of NIH Study Section, Community Influences on Health Behavior and an appointed member of the American Academy of Pediatrics Tobacco Consortium. She is also a member of the West Virginia University Hall of Fame (College of Education and Human Services), a distinguished alumni award.