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Affinity Capture Device
Courtesy of Deborah Kelly
Affinity capture devices produced on commercial silicon nitride microchips (a) contain viewing windows (b) that allow an electron microscope beam to penetrate to the specimen level. Devices can be functionalized with lipid monolayers (c) containing Ni-NTA heads groups (red circles) that bind to His-tagged protein targets (red complexes) (d).
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