Regeneration & Rehabilitation Related Studies

Baby Children with Hemiparesis Arm and Hand Movement Project (CHAMP) Study

This is a research study comparing three highly promising forms of therapy for infants and toddlers who have a diagnosis of hemiparetic cerebral palsy. Children who meet study eligibility criteria at one of the two clinical sites - Roanoke, Virginia, and Columbus, Ohio - will be invited to enroll.

  • Participation involves:
    • Assessment of each child prior to treatment, close monitoring of the child's progress during treatment, and post-evaluation at the end of therapy, as well as 6 and 12 months later.
    • Questions for parents about their thoughts and feelings concerning the therapy condition that they and their children are experiencing.
  • No charge for therapy provided.
  • Child must be between 6 and 24 months old
  • Child must have a medical diagnosis of cerebral palsy
  • Child must have a significant impairment in the use of an upper extremity
  • Child must be able to communicate basic needs and interact in a playful way with a familiar adult
  • Child must have one or both parents who are willing to participate in learning how to provide at-home therapy activities that will involve one hour a day over a four-week period

For more information, visit http://labs.vtc.vt.edu/nmrc or call Dr. Stephanie DeLuca in Roanoke at 540-526-2098 or Dr. Andrew Persch in Columbus at 614-685-9217.

Children with Hemiparesis Arm and Hand Movement Project (CHAMP) Study

This is a research study comparing the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy, also known as hemiparetic cerebral palsy. Children who meet study eligibility criteria at one of the three clinical sites - Roanoke, Virginia; Charlottesville, Virginia; and Columbus, Ohio - will be invited to enroll.

  • Participation involves:
    • Assessment of each child prior to treatment, close monitoring of the child's progress during treatment, and post-evaluation at the end of therapy, as well as 6 and 12 months later.
    • Questions for parents about their thoughts and feelings concerning the therapy condition that they and their children are experiencing.
  • No charge for therapy provided.
  • Child must be between 2 and 8 years old (up to ninth birthday)
  • Child must have a neuromotor impairment that mostly affects one side of the body.
  • Child must have cerebral palsy or an acquired brain injury prior to the age of two.
  • Child must be able to participate in four weeks of therapy.

For more information, visit http://labs.vtc.vt.edu/nmrc or call Dr. Stephanie DeLuca in Roanoke at 540-526-2098 or Dr. Andrew Persch in Columbus at 614-685-9217 or Jodi Darring in Charlottesville at 434-982-3808.

Episodic future thinking and real-time fMRI

This is a research study aiming to assess your imagination skills inside an fMRI scanner. We will ask you to complete several computerized tasks and a few computerized survey questionnaires. An example of the computerized task might ask you to choose between delayed and immediate imagined amounts of money. For example, you may be asked to choose between $1000 in a month’s time or $500 right now.

You will also be asked to come up with future or current events during a short interview. For example, “Describe what you would do with $100 in 6 months” or “Describe something you do with $50 today.” You will also complete several tasks while in an fMRI scanner that will last approximately one hour. You will be asked to try to imagine yourself in different situations.

  • Compensation is up to $80 for a 3-hour session
  • Participation involves:
  • Decision making tasks
  • Imagination skills tasks
  • fMRI brain scan – you’ll receive a CD with images of your brain to take home!
  • This is not a treatment study
  • Pregnant females are not eligible
  • All information is confidential
  • Travel compensation to Roanoke may be provided
  • If you qualify, total compensation based on extent of participation in the study
  • Must be between 21 and 65 years of age
  • Participants may be invited for repeated sessions

If you are interested in participating, please contact a representative at (540) 315-0205 or at arrc@vtc.vt.edu. You may also complete an online screening at http://j.mp/2eez4J0.

Functional MRI Study of Traumatic Experiences Among Veterans

The Virginia Tech Carilion Research Institute is currently recruiting OEF/OIF veterans for research studies. These studies use functional MRI to understand how deployment can impact the biology of the brain. Why participate? Deployment experiences can have a profound impact on the lives and well-being of the people who experience them. While the effects can be a tremendous burden both for those experiencing the difficulties and for their loved ones, little is known about the causes and treatments of deployment-related difficulties. For this study, we are interested in veterans who either have or have not experienced symptoms of post-traumatic stress disorder, depression, or traumatic brain injury.

Contact vets@vtc.vt.edu or 540-526-2091

Human Neuroimaging Laboratory—General Recruitment

The Human Neuroimaging Laboratory accepts volunteers interested in being added to the general recruitment pool for a range of studies related to human cognition and decision-making.

Eligibility: Healthy adults aged 18 to 64

Primary goal: To advance human brain research through behavioral and fMRI studies

Institute sponsor: Human Neuroimaging Laboratory

Compensation: varies by study

Visit Subject Sign Up, email us at signup@vtc.vt.edu, or call 540-526-2034

Human Neuroimaging Laboratory—Roanoke Brain Study

The Roanoke Brain Study is a partnership between the greater Roanoke Valley community and leading scientists to explore the cognitive, behavioral, and genetic factors that affect human decision-making. The study combines novel approaches in functional brain imaging, computational psychiatry, and genetics to study features of decision behavior and how those behaviors change in people over the course of their lives. The aim is to create a global information resource for scientists, physicians, patients, and policy makers seeking insight into processes of decision-making to facilitate healthier lives. The primary task will be an fMRI scan, a non-invasive imaging tool that allows us to capture images of the brain and its activity while volunteers view images, play games, or interact with other people. Volunteers may also be asked to provide a small DNA sample, fill out questionnaires, play simple games on the computer, or interact with other people inside or outside the MRI scanner.

Eligibility: Healthy adults aged 18 to 85

Compensation: Approximately $100

Primary goal: To understand how genes and environment contribute to brain strategies for decision-making in all aspects of life.

Institute sponsor: Human Neuroimaging Laboratory

Study timeframe: Ongoing

To volunteer: Visit Roanoke Brain Study for more information.

Volunteers may sign up for the Roanoke site or the Blacksburg site

MRI Research Study on Adolescents

Volunteers are needed for a neuroimaging study to better understand how the adolescent brain makes decisions.

Who is eligible? People who:

  • Are between 15 and 17 years old
  • Are not claustrophobic
  • Do not have permanent metal implants
  • Can commit to participating in Roanoke, Virginia

Participants will:

  • Participate fill out questionnaires
  • Play computer games during MRI scans
  • Receive a copy of their brain scan
  • Be compensated $70-110 for participating

If you meet the above requirements and are interested in participating, contact Brennan Delattre at 540-526-2068 or participate@vtc.vt.edu. Please include "Adolescent Study" in the subject line.