Harry Dorn collaboration to target neuroblastoma detection and treatment

Harry Dorn, Ph.D.

Harry Dorn, Ph.D.

Harry Dorn, a professor at the Virginia Tech Carilion Research Institute, has received a grant in collaboration with Anthony Sandler of the Children’s National Medical Center to develop better treatments and diagnosis for neuroblastoma. The award is part of a new partnership between the Virginia Tech Carilion Research Institute, the Children’s National Medical Center, and George Washington University to seed seven yearlong projects in hopes that they will result in publications and the submission of inter-institutional research grant applications to federal agencies.

Neuroblastoma is a common pediatric extracranial tumor in which most cases are high-risk with poor prognoses. The collaboration will target two molecular markers that the Sandler Lab has identified as being highly expressed in neuroblastoma cells. The Dorn Lab has demonstrated the ability to create metallofullerenes – spherical carbon structures with metal atoms at their cores – that selectively bind with these molecular markers. It is the hope of these two laboratories that their collaboration will be able to use these two developments to produce a reliable early detection diagnoses method and perhaps novel therapies for neuroblastoma.