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Yuzhi Chen, PhD

Yuzhi Chen, PhD

The Function of the Amyloid Precursor Protein and Its Implications in the Pathogenesis of Alzheimer’s Disease


October 17, 2011, 4:00 p.m. to 5:00 p.m.


Yuzhi Chen, PhD

Assistant Professor, Department of Geriatrics, Department of Neurobiology and Developmental Sciences, Reynolds Institute on Aging, The University of Arkansas for Medical Sciences, Little Rock, Arkansas


Fralin Biomedical Research Institute, R1059
2 Riverside Circle, Roanoke, VA 24016

Alzheimer’s disease is the leading cause of dementia affecting millions of Americans. Dr. Chen’s research investigates how the normal physiological functions of the amyloid precursor protein (APP) and its proteolytic products are derailed in Alzheimer’s disease. She will present her results showing that APP interacts with the ubiquitination pathway and discuss how loss of Aβ40 may contribute to Alzheimer’s disease by affecting neurogenesis.

Selected Publications

About the Speaker:

Yuzhi Chen's research focuses on the roles of protein ubiquitination in Alzheimer’s disease and mental retardation.

Additional Details

This is a free event. The host is Michael Friedlander, PhD. For more information, please call 540-526-2070, or send an e-mail.

Map and Parking

This map shows where the Fralin Biomedical Research Institute is located in Roanoke, VA at 2 Riverside Circle.

Parking is available in the parking garage across the street.

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Event Type