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Yuzhi Chen, PhD

Yuzhi Chen, PhD

Dysfunction of Ubiquitination as a Potential Pathogenic Mechanism of Alzheimer’s Disease


October 18, 2011, 1:00 p.m. to 2:00 p.m.


Yuzhi Chen, PhD

Assistant Professor, Department of Geriatrics, Department of Neurobiology and Developmental Sciences, Reynolds Institute on Aging, The University of Arkansas for Medical Sciences, Little Rock, Arkansas


Fralin Biomedical Research Institute, R1059
2 Riverside Circle, Roanoke, VA 24016

A major goal of Dr. Chen’s research is aimed at a molecular understanding the regulation of ubiquitination in neurons using both animal models and human tissue. She will discuss her future research plans investigating how the amyloid precursor protein interacts with the ubiquitination pathway, specifically through Cul5 and Cul4B ubiquitin ligases. She will also consider how downstream effectors may be targeted for disease interventions.

Selected Publications

About the Speaker:

Yuzhi Chen's research focuses on the roles of protein ubiquitination in Alzheimer’s disease and mental retardation.

Additional Details

This is a free event. The host is Michael Friedlander, PhD. For more information, please call 540-526-2070, or send an e-mail.

Map and Parking

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Event Type