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Robert Kimberly, MD
Genetic Architecture in Autoimmunity: Shaping the Response to Stimulation
Howard L. Holley Professor of Medicine, Senior Associate Dean for Research, and Director of the Comprehensive Arthritis, Musculoskeletal and Autoimmunity Center, University of Alabama at Birmingham School of Medicine
2 Riverside Circle, Roanoke, VA 24016
This seminar will review the current insights into the heritable genetic variation in human immune system molecules that influence our risk for developing autoimmune disease. Antibody formation as part of the humoral immune response and the interaction of these antibodies with their cognate receptors are central to immune host defense. Mechanisms that enhance our response to vaccines also increase the risk of autoimmune disease.
About the Speaker:
Robert Kimberly, MD, is the Howard L. Holley Professor of Medicine at the University of Alabama, Birmingham, where he is also the senior associate dean for research and director of the UAB Comprehensive Arthritis, Musculoskeletal and Autoimmunity Center. A rheumatologist and immunologist, Dr. Kimberly conducts research aimed at understanding the role of genetic factors in the normal function of the immune system and in the development of immunological diseases such as systemic lupus erythematosus, systemic vasculitis, and rheumatoid arthritis.