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Zhi Sheng, PhD

Zhi Sheng, PhD

The Role of Autophagy in Glioblastoma


September 7, 2011, 12:00 p.m. to 1:00 p.m.


Zhi Sheng, PhD

Postdoctoral Fellow, Howard Hughes Laboratory, Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, Massachusetts


Fralin Biomedical Research Institute, R1059
2 Riverside Circle, Roanoke, VA 24016


A shuttle to Roanoke will depart from Blacksburg in front of Burruss Hall at 11 a.m., returning at 2 p.m.

Autophagy has been shown to be important in cancer formation and cancer therapeutic resistance. Dr. Sheng will discuss his future research plans for elucidating the role of autophagy in glioblastoma multiforme. He will consider how to elucidate the mechanisms that underpin the role of autophagy in the formation and therapeutic resistance of glioblastoma multiforme. This approach will be evaluated in the context of developing novel effective therapies. Three specific goals of Dr. Sheng’s future research plans will be presented and discussed: the characterization of genes that regulate autophagy in glioblastoma; the determination of the role of autophagy in the genesis of glioblastoma; and the elucidation of the role of autophagy in therapeutic resistance of glioblastoma.

Selected Publications

About the Speaker:

Dr. Sheng’s research focuses on molecular mechanisms of how glial cells in the brain become malignant, acquiring sustained proliferation capacity and escaping death, cancer specific autophagy-signaling pathways and glioblastoma specific survival pathways.

Additional Details

This is a free event. The host is Michael Friedlander, PhD. For more information, please call 540-526-2070, or send an e-mail.

Map and Parking

This map shows where the Fralin Biomedical Research Institute is located in Roanoke, VA at 2 Riverside Circle.

Parking is available in the parking garage across the street.

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