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John Scott, PhD
Cell Signaling in Space and Time
Edwin G. Krebs - Hilma Speights Professor of Cell Signaling and Cancer Biology, Department of Pharmacology, University of Washington School of Medicine, Seattle, Washington
2 Riverside Circle, Roanoke, VA 24016
Intracellular signal transduction events are precisely regulated in space and time. This is achieved in part by A-kinase anchoring proteins, or AKAPs, which tether signaling enzymes such as protein kinases and phosphatases in proximity to selected substrates.