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Piotr Kraj, DVM, PhD
Is Connexin 43 a Pivot Regulating T Cell Differentiation and Activation?
Associate Professor, Center of Biotechnology and Genomic Medicine, Georgia Health Sciences University
2 Riverside Circle, Roanoke, VA 24016
Piotr Kraj, DVM, PhD, Associate Professor at the Center of Biotechnology and Genomic Medicine at Georgia Health Sciences University in Augusta will present a special seminar entitled, “Is Connexin 43 a Pivot Regulating T Cell Differentiation and Activitation?”
Dr. Kraj's research is on uncovering cellular and molecular mechanisms of immune system with special emphasis on processes that regulate the development and functions of conventional and regulatory T cells. He is interested in how immune tolerance is established and preserved in healthy individuals and how tolerance mechanisms are subverted or alleviated to permit growth of tumor cells. Dr. Kraj is particularly focused on the involvement of Connexin 43 in the generation of regulatory CD4+ T cells in the thymus and in the interplay between stromal cells and components of the innate and adaptive immune system in a mouse model of prostate cancer. The goal of his studies is to reveal and exploit novel mechanisms of immune regulation to overcome challenges facing immunotherapies of cancer.
About the Speaker:
Dr. Kraj received his DVM in 1987 and his PhD from the Ludwik Hirszfeld Institute of Immunology and Experimental Therapy in Biological Sciences in 1995.