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Clare M. Waterman, PhD
Integrating Actin and Adhesion Dynamics in Cell Migration
NIH Distinguished Investigator, Laboratory of Cell and Tissue Morphodynamics, National Heart, Lung, and Blood Institute, National Institutes of Health
2 Riverside Circle, Roanoke, VA 24016
Dr. Waterman will discuss a variety of advanced techniques to study cytoskeletal and adhesion dynamics measuring minute forces. These include traction force microscopy that allows for the measurement of the forces between the cell and the extracellular matrix while fluorescence speckle microscopy allows measurement of protein dynamics. By correlating the forces with protein dynamics under different molecular perturbations, Dr. Waterman’s work bridges the intellectual gap between molecular signaling and physical changes that are the final effectors of movement.