Leslie LaConte

Leslie LaConte, Ph.D.

Research Associate Professor

Assistant Dean for Research, School of Medicine

Associate Professor, Basic Science Education, School of Medicine


Office phone: 540-526-2084

Office location: R2127

Email address: lacon001@vtc.vt.edu

Dr. Leslie LaConte's research interests lie in the field of structural biology. Working with Dr. Konark Mukherjee, she is currently investigating the impact that missense mutations have on the structure and function of CASK, a putatively synaptic protein associated with microcephaly and developmental delay, using both computational and cell biological tools.

As assistant dean for research for the Virginia Tech Carilion School of Medicine, LaConte is responsible for development and implementation of the school's research education curriculum and horizontal and vertical integration of research domain curricular elements across all four years and with the school’s other three domains. She reports to the senior dean for research and the senior dean for academic affairs.

Education and Training

  • Georgia Institute of Technology: Postdoctoral Fellowship
  • University of Minnesota: Ph.D. , Biochemistry

Selected Publications

McKell A, LaConte LEW, McDonald SM. (2017). Temperature-sensitive lesion in the N-terminal domain of the rotavirus polymerase affects its intracellular localization and enzymatic activity. Journal of Virology .

LaConte LE, Chavan V, Liang C, Willis J, Schönhense EM, Schoch S, Mukherjee K. (2016). CASK stabilizes neurexin and links it to liprin-a in a neuronal activity-dependent manner. Cell Mol Life Sci : [Epub ahead print] doi:10.1371/journal.pone.0088276.

LaConte LEW, Chavan V, Mukherjee K. (2014). Identification and glycerol-induced correction of misfolding mutations in the X-linked mental retardation gene CASK. PLOS ONE .