Poelzing Lab
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Steven Poelzing, Ph.D. , homeProfessor
Led by principal investigator Steven Poelzing, Ph.D., the Poelzing Lab studies the processes of electrical activity between cardiac myocytes and connexin proteins and how mutations are linked to sudden cardiac death, as well as diseases such as heart failure, ischemia, or diabetes. The Poelzing Lab also seeks to determine how pathological insults such as cardiac inflammation and edema modulate the risk of sudden death in the young and how age changes this relationship.
Techniques
- High-resolution optical mapping
- Isolated cellular electrophysiological measurements
- Immunohistochemistry
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William Adams , bioGraduate Student, Translational Biology, Medicine and Health
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Chandra Bain , bioResearch Project Associate
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Gregory S. Hoeker, Ph.D. , bioResearch Assistant Professor
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Katie Lee , bioMedical Student, Virginia Tech Carilion School of Medicine, '26
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Rowan Maisonneuve , bioResearch Assistant
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Mark Warren, Ph.D. , bioResearch Assistant Professor
Social Media
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Article ItemMedical student’s research investigates the heart of the matter , article
When Katie Hardin was considering medical schools, it was the extensive research focus of the Virginia Tech Carilion School of Medicine that won her heart. Her research into calcium deposits in the cardiac intercalated disk may be a step toward preventing lethal arrhythmias in the future.
Date: Mar 14, 2023 -
Article ItemPhilanthropy supports pilot projects to take on health challenges such as heart disease, diabetes, cancer, stress, and chronic pain , article
Giving Day contributions to the Fralin Biomedical Research Institute at VTC have double the impact, unlocking $20,000 to the Seale Innovation Fund to accelerate innovation
Date: Feb 15, 2023 -
Article ItemTranslational Biology, Medicine, and Health Graduate Program’s entering class comprises a rich mix of students , article
The new class includes 11 women pursuing doctoral degrees and three students in the new M.D.+Ph.D. track. The program enrolled its first class in 2014.
Date: Oct 10, 2022 -
Article ItemFralin Biomedical Research Institute expands Summer Undergraduate Research Fellowship program , article
More than 30 undergraduate and high school students worked behind the curtain of biomedical research this summer at the Fralin Biomedical Research Institute at VTC.
Date: Aug 16, 2022 -
Article ItemFralin Biomedical Research Institute at VTC Center for Vascular and Heart Research holds retreat to catalyze collaboration , article
The daylong retreat at The Hotel Roanoke & Conference Center and on the research institute campus included presentations by research teams about their lab’s key techniques, competencies, and equipment.
Date: Jul 21, 2022 -
Article ItemScientists detect deadly arrhythmia trifecta: Salt, swelling, and leaky sodium channels , article
Cardiovascular researchers led by Steven Poelzing at Virginia Tech’s Fralin Biomedical Research Institute at VTC have published a new study describing how deadly arrhythmias arise from elevated sodium levels, heart tissue irritation and swelling, and sodium channel abnormalities associated with Long QT syndrome.
Date: May 24, 2022 -
Article ItemRare disease research gives families hope, ‘vital’ to advancing medicine , article
Rare diseases afflict 300 million people worldwide. Fralin Biomedical Research Institute at VTC researchers are bridging a gap in scientific knowledge by studying some of the diseases that together add up to a formidable public health challenge. Feb. 28 marks the 14th international Rare Disease Day.
Date: Feb 28, 2022 -
Article ItemTBMH doctoral student crowned first-ever Miss Virginia Volunteer , article
Breana Turner, a first-year student in the Translational Biology, Medicine, and Health Graduate Program at Virginia Tech, was recently awarded the title, earning a $10,000 scholarship.
Date: Aug 24, 2021 -
Article ItemTBMH graduate student awarded NIH grant to study diagnosis and treatment of genetic heart disease , article
Grace Blair, who works in the lab of Steve Poelzing at the Fralin Biomedical Research Institute at VTC, was awarded a two-year grant under the National Institutes of Health's Ruth L. Kirschstein Predoctoral Individual National Research Service Award.
Date: Aug 12, 2021 -
Article ItemMind the gap: Heart cells cozy up to prevent deadly arrhythmias, Fralin Biomedical Research Institute researchers find , article
Steven Poelzing, associate professor at the Fralin Biomedical Research Institute at VTC, leads a team of cardiovascular scientists studying electrical conduction in the heart. Poelzing’s lab recently published a study that showed increasing sodium and calcium levels in the bloodstream helps keep dangerous heart rhythms, triggered by potassium overdose, at bay.
Date: May 03, 2021 -
Article ItemTBMH graduate program office earns gold certification for sustainability efforts , article
The translational biology, medicine, and health graduate program, part of Virginia Tech’s Graduate School, is the first university office to receive a Gold Certification for sustainability efforts through the Virginia Tech Office of Sustainability.
Date: Jan 19, 2021 -
Article ItemFralin Biomedical Research Institute scientists provide new evidence of elusive electrical pathway in the heart , article
Associate Professor Steven Poelzing and Research Assistant Professor Gregory Hoeker, of the Fralin Biomedical Research Institute at VTC, recently published a study that helps explain why our classical understanding of heart beats and the mathematical models don’t add up.
Date: Nov 12, 2020 -
Article ItemFralin Biomedical Research Institute at VTC scientists discover compound that could shield heart tissue , article
Imagine there was a drug that you could take soon after a heart attack that could reduce damage by protecting healthy heart muscle tissue.
Date: Aug 19, 2019 -
Article ItemInternational scientists to plug into cellular signals at Fralin Biomedical Research Institute conference , article
To explore potential sources of cellular electrical communication, the Fralin Biomedical Research Institute at VTC is hosting the world’s first Ephaptic Coupling Conference in Roanoke, Virginia, from May 5 to 7.
Date: Apr 29, 2019 -
Article ItemVTCRI scientist awarded new federal grant to study cardiac conduction in health, disease , article
The grant will fund Steven Poelzing’s research into a heart mutation, known as a gain-of-function mutation, that can lead to sudden cardiac death and other heart conditions.
Date: Sep 17, 2018 -
Article ItemThe heart: digital or analog? VTCRI researchers shed dramatic new light on disorders of heart bioelectricity , article
Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart — a discovery that potentially can lead to new insight into medical problems, such as heart arrhythmia and sudden cardiac death.
Date: Aug 27, 2018 -
Article ItemVTCRI scientists, Carilion clinicians first to identify perinexus in human heart , article
The research team was led by Steven Poelzing, an associate professor at the Virginia Tech Carilion Research Institute, and Soufian AlMahameed, who was a clinician associate professor at the Virginia Tech Carilion School of Medicine and the director of Carilion Clinic’s Center for Atrial Fibrillation at the time of data collection.
Date: Jun 18, 2018 -
Article ItemTBMH graduate students land elusive National Institutes of Health fellowships , article
Doctoral students Tristan Raisch and Carissa James have won National Institutes of Health research fellowships aimed at protecting people with heart problems.
Date: Jan 08, 2018 -
Article ItemMedical honor society organizes first-ever idea exchange with biomedical researchers , article
Two members of the Virginia Tech Carilion School of Medicine’s Alpha Omega Alpha national medical honor society recently organized an event that brought clinicians and biomedical researchers together to learn from each other and formulate ideas for future collaborations.
Date: May 05, 2017 -
Article ItemVirginia Tech Carilion Research Institute scientist awarded $2.1 million to fight heart disease , article
Steven Poelzing, an associate professor at the institute, will lead a research team to investigate how the microscopic spaces surrounding heart cells affect connections called gap junctions, which allow electrical impulses and small molecules to pass between cells.
Date: Jan 10, 2017 -
Article ItemThird class joins Virginia Tech’s translational biology, medicine, and health doctoral program , article
The doctoral program is the Virginia Tech Graduate School’s largest interdisciplinary program, with more than 200 members of Virginia Tech’s Faculty of Health Sciences teaching and mentoring the students.
Date: Aug 23, 2016 -
Article ItemVirginia Tech Carilion Research Institute scientist honored with Heart Rhythm Society Clinical Research Award , article
He will use the award funds to study, in a rodent model, how the composition of fluids administered to patients who have suffered cardiac arrest or myocardial infarction affects whether or not they survive and how well they recover from the event.
Date: Jul 27, 2016 -
Article ItemPersonalized saline may provide solution to heart death , article
Virginia Tech Carilion Research Institute scientists found that saline solution composition can affect cardiac response differently.
Date: May 29, 2015 -
Article ItemInaugural heart school events will get rescheduled , article
The public is invited to learn more about heart development and current cardiovascular research during Virginia Tech Carilion Research Institute’s first heart school, held as part of American Heart Month.
Date: Feb 23, 2015 -
Article ItemVirginia Tech Carilion Research Institute sets a new pace in heart research , article
The Virginia Tech Carilion Research Institute, well known for its innovative, world-class brain research, is launching a major new initiative in cardiovascular research.
Date: May 20, 2014
Recent Media Coverage
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Redirect ItemMedical Xpress: Heart cells cozy up to prevent deadly arrhythmias , redirect Date: May 04, 2021
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Redirect ItemScienmag: Heart Cells Cozy Up To Prevent Deadly Arrhythmias , redirect Date: May 04, 2021
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