Cancer and Aging
Dr. DePinho will discuss recent discoveries that have led to better methods of early cancer detection, improved cancer patient care, and new cancer drugs. Such discoveries can come from a range of fields, including developing new biomarkers, discovering new cancer genes, uncovering new stem cell biology, and genetically engineering new mouse models to study cancer in humans.
In a notable discovery, Dr. DePinho showed a link between advancing age and increasing risk in cancer. He established that three factors - telomere dysfunction, an impaired ability of a cell to repair DNA damage, and the continued renewal of the epithelial layer of tissue that covers organs - all unite to cause rearrangements in the DNA that drive the genesis of many common cancers. To learn more about telomeres and how aging pushes the human body toward cancerous tumors, be sure to attend.
A public reception will precede this event in the VTC Cafe at 5 p.m.