Upcoming events

  • Dopamine Neuron Regulation and its Disruption in Schizophrenia and Depression

    Speaker: Anthony Grace, PhD, Distinguished Professor of Neuroscience, Professor of Psychiatry-Psychology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

    The brain's dopamine system has been implicated in a number of psychiatric disorders ranging from schizophrenia to depression; however, the nature of the disruptions leading to such diverse conditions is ...

  • Hypothesis-Generating Research and Predictive Medicine

    Speaker: Les Biesecker, MD, Senior Investigator, Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland

    While the hypothesis testing (research) and differential diagnostic (clinical) paradigms are effective and should continue, the availability of large scale medical sequencing begs the question as to whether these need ...

  • The Molecular Toolkit of Viral Hemorrhagic Fevers

    Speaker: Erica Ollmann Saphire, PhD, Professor, Department of Immunology and Microbial Science, The Scripps Institute, San Diego, California

    Viruses must achieve a number of functions in their lifecycles, often using compact genomes. Dr. Ollmann Saphire will describe her laboratory's discovery that Ebola virus extends the functional complexity of ...

  • Clinical Genomics = Personal Genomes + Clan Genomics

    Speaker: James Lupski, MD, PhD, Cullen Endowed Chair in Molecular Genetics, Professor, Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas

    Following the “finished” euchromatic, haploid human reference genome sequence, clinical implementation of genome-wide assays for genomic disorder associated copy number variants (CNVs) has demonstrated the tremendous utility of capturing rare, ...

  • A View of Cortex from the Thalamus

    Speaker: S. Murray Sherman, PhD, Professor and Chairman of Neurobiology, University of Chicago, Chicago, Illinois

    Dr. Sherman's talk will provide evidence that cortical areas are often connected in parallel by direct and transthalamic pathways. There will then follow speculation regarding why this parallel arrangement exists, ...

  • Modern Treatment of Alcoholism

    Speaker: Charles P. O'Brien, MD, PhD, Kenneth E. Appel Professor of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Member, National Academy of Sciences, Member, Institute of Medicine

    Alcoholism is a common, chronic disease with strong genetic influence. Modern neuroscience has uncovered much about the underlying mechanisms of this devastating condition, but few physicians are aware that effective ...

  • Synapses, Muscular Dystrophy, and Brain Disorders

    Speaker: Lin Mei, MD, PhD, Director of Institute of Molecular Medicine and Genetics, Professor of Neurology, Georgia Regents University, Augusta, Georgia

    The human brain contains billions of neurons to receive and integrate a host of electrical and biochemical signals. Efficiency in communication among neurons is made possible by synapses, contacts formed ...

  • High-Throughput Self-Interaction Chromatography: Applications Protein Solubility & Stability

    Speaker: Larry DeLucas, OD, PhD, Director, Center for Biophysical Sciences and Engineering, University of Alabama at Birmingham, Birmingham, Alabama

    The physical stability of a protein generally depends on suppression of aggregation. In either case, it is ultimately the protein-protein interactions in the specified solvent condition that dictates the process ...

  • The Pathophysiologic Mechanisms of Allergic Diseases

    Speaker: Hirohito Kita, MD, Walter and Leonore Annenberg Professor of Pulmonary Medicine and Professor in Medicine and Immunology, Mayo Clinic, Rochester, Minneapolis

    Immunity and inflammatory processes play important roles in the pathophysiology of allergic diseases, such as bronchial asthma, hay fever, atopic dermatitis, and chronic rhinosinusitis. Dr. Kita will discuss his research ...

  • Deciphering the Mechanisms of Actin Filament Architecture in Striated Muscle

    Speaker: Carol Gregorio, PhD, Director of the Molecular Cardiovascular Research Program, Head of the Department of Cellular and Molecular Medicine, Co-Director of the Sarver Heart Center, Luxford/Schoolcraft Endowed Professor of Cardiovascular Disease Research, University of Arizona School of Medicine, Phoenix, Arizona

    Striated muscle cells contain arrays of protein filaments assembled into contractile units that are nearly crystalline in structure. Since efficient contraction is predicated upon accurate overlap of thin and thick ...

  • Influenza Virus Host Tropism

    Speaker: Adolfo Garcia-Sastre, PhD, Professor of Medicine, Infectious Diseases, Professor of Microbiology, Director of the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine and Hospital, New York, New York

    Dr. Garcia-Sastre will discuss the ability of specific animal influenza viruses to infect humans and the concerns about pandemic potential. His laboratory is studying the determinants associated with increased human ...

  • Pulmonary Hypertension: Has It Become a “Forgettable” Disease?

    Speaker: Robert Bourge, MD, Professor of Medicine, Radiology, and Surgery, Vice-Chair for Clinical Affairs and Development, Department of Medicine, E.A. and Abbie Drummond Endowed Chair in Cardiovascular Medicine, University of Alabama at Birmingham

    Dr. Bourge will lead an interactive discussion of the methods to screen, diagnose, and treat this previously almost uniformly fatal disease, concentrating on recent advances in disease detection and therapy.

  • Epigenetics and the Immune System

    Speaker: Jeremy Boss, PhD, Professor and Chair, Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia

    Epigenetics refers to the processes by which cells inherit information that dictate their ultimate properties and functions. Dr. Boss's seminar will focus on how these processes control the ability of ...

  • Unraveling the Pathogenesis of Respiratory and Enteric Viruses in Normal and High-Risk Populations

    Speaker: Stacy Schultz-Cherry, PhD, Faculty Member and Associate, St. Jude's Children's Hospital, Center for Excellence in Influenza Research and Surveillance and the World Health Organization Collaborating Center, Memphis, Tennessee

  • Imaging Mammalian Heart and Vessel Development: Insights into Vascular Remodeling and Congenital Heart Disease

    Speaker: Mary Dickinson, PhD, Professor, Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas

    Dr. Dickinson's seminar will describe insights derived from the use of optical imaging and microscopy to study the early function of the mouse heart, mechanical forces needed to promote outward ...

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